https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Ovarian cancer risk in Polish BRCA1 mutation carriers is not associated with the prohibitin 3' untranslated region polymorphism https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4382 G, 4154delA) including 127 ovarian cases and 127 unaffected controls who had both breasts and ovaries intact. Controls were matched to cases by year of birth and BRCA1 mutation. Genotyping analysis was performed using PCR-based restriction fragment length polymorphism analysis. Odds ratios (OR) were calculated using conditional and penalized univariable and multivariable logistic regression. Results: A comparison of the genotype frequencies between cases and controls revealed no association of the PHB 3'UTR _CT+TT genotypes with ovarian cancer risk (ORadj 1.34; 95% CI, 0.59–3.11). Conclusion: Our data suggest that the PHB 3'UTR polymorphism does not modify ovarian cancer risk in women carrying one of the three Polish BRCA1 founder mutations.]]> Wed 11 Apr 2018 14:48:22 AEST ]]> BRIP1, PALB2, and RAD51C mutation analysis reveals their relative importance as genetic susceptibility factors for breast cancer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:12510 Sat 24 Mar 2018 08:18:42 AEDT ]]> The virtual consultation: practitioners' experiences of genetic counseling by videoconferencing in Australia https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10513 Sat 24 Mar 2018 08:13:59 AEDT ]]> Comparison of genomic abnormalities between BRCAX and sporadic breast cancers studied by comparative genomic hybridization https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:261 Sat 24 Mar 2018 07:42:57 AEDT ]]>